Bio Span+ Trans-Resveratrol Longevity Supplements Overview
This unique complex of bio enhanced trans-resveratrol and potent polyphenols and anthocyanins is formulated specifically to fight aging at both the genetic and metabolic levels. A patent pending longevity formulation of advanced phytoalexins, antioxidants & potent polyphenols designed to both activate longevity genes & reduce free radical damage. Bio Span+ is the only scientifically formulated resveratrol-based supplement which provides a truly synergist blend of longevity compounds in one capsule. Bio Span+ contains SirT-1 activators, telemerase precursors, and neurotropic agents, the three major anti-aging bioceuticals. The objective of Biotivia´s scientists was to create a totally natural product which attacks aging at the metabolic, epigenetic, and neural levels. This translates into slower physical, cellular and mental aging.
Ingredients
Regenerate, Rejuvenate and Restore
Trans-Resveratrol 75%, 200mg -- This ingredient alone would make an extraordinary product. Bio-enhanced natural Resveratrol modulates the benefits of the other polyphenols contained in this complex and activates the SirT longevity genes.
Silymarin 200mg -- A second SirT gene activator that complements trans-resveratrol. Extracted from blessed milk thistle, Silymarin supports healthy liver function and modulates blood glucose levels. Chosen over Quercetin, which actually suppresses SirT activation and interferes with the important resveratrol metabolites.
Astralagus 300mg -- Considered to be the most promising longevity compound after resveratrol. Some studies indicate that this extract may have telemere protective properties. Also supports immune system, and may increase the body's resistance to common viruses. Bio Span+ contains the two essential Astragalosides of this compound including the rare Astragaloside IV molecule.
Curcumin 300mg -- A uniquely effective polyphenol that acts as a free radical scavenger and antioxidant, inhibiting lipid peroxidation and oxidative DNA damage. Curcumin's beneficial properties are well established and supported by a wealth of peer-reviewed published data. Standardized to minimum 96% active curcumins.
Per serving of 2 Vcaps.
BioSpan+ is totally natural, it contains no animal products, no fillers and no silica or titan dioxide.
Why Choose Bio Span+
Bio Span+ is the only scientifically formulated resveratrol-based supplement which provides a truly synergistic blend of longevity compounds in one capsule. Bio Span+ contains SirT-1 activators, telemerase precursors, and neurotropic agents, the three major anti-aging bioceuticals. The objective of Biotivia´s scientists was to create a totally natural product which attacks aging at the metabolic, epigenetic, and neural levels. This translates into slower physical, cellular and mental aging.
Why Bio Span+ is Unique
The Trans-resveratrol contained in Bio Span + is a 50/50 blend the same bio-enhanced proprietary full-spectrum found in Bioforte and the pure Trans-resveratrol we put in Transmax. This provides all of the important glucosides of the Polygonum plant including Polydatin, and an extra helping of the pure trans-resveratrol isomer. We combine the resveratrol with concentrated extract of Curcumin, a compound shown to stimulate the growth of new neurons, as well as Silymarin, an extract of the Blessed Milk Thistle plant that, like trans-resveratrol, is a SirT-1 activator, and the two Astragalosides which researchers have found to have telemerase stimulation properties. One other company is selling a therapy based upon Astragalosides IV, one of the compounds in Bio Span+, for around £20,000 for a one year program of supplementation and telemere length testing.
Why Bio Span+ Trans-Resveratrol Longevity?
Although resveratrol is the most publicized new longevity compound, it alone will not address your entire need for advanced nutrition; hence Bio Span+ was developed. Bio Span+ was designed to complement the life extension properties of resveratrol by adding concentrated polyphenols and the SirT1 Activator silymarin, along with curcumin, and the two critical astragalosides of Astralagus which are believed by many scientists to have telemere protective properties. No other product currently being manufactured compares to Bio Span+ in its potential for enhancement of longevity.
Why did Biotivia Choose Not to Include Quercetin?
They have devoted quite a bit of study and research to quercetin's effect on resveratrol and resveratrol's metabolites and the issue of SirT-1 activation. The conclusion is that the most recent and best designed studies, including a study by one company that actually puts quercetin in their product, conclude that quercetin strongly inhibits the metabolites of resveratrol and suppresses SirT1 activation. Quercetin has been shown in numerous studies to interfere with the beneficial metabolites of resveratrol. These metabolites, particularly resveratrol glucuronide, resveratrol sulphate and picead possess important health properties. Studies also confirm that enterohepatic recirculation (recirculation by the liver) of these metabolites contributes significantly to the enhanced exposure of resveratrol in the tissues of mammals. Furthermore, quercetin's undesirable SirT-1 suppression clearly rules it out as an ingredient in any longevity product.
If Biotivia scientists believed that quercetin would improve their products in a substantive way it would be in their interest to add it to the products. From an economic standpoint this would also benefit them, as quercetin is far less costly than the high-grade resveratrol used in their supplements. A recent study by the makers of Longevinex strongly confirms this conclusion that quercetin inhibits SirT1 and possibly the other sirtuins as well. In this study a combination of resveratrol and quercetin along with the filler oat bran actually reduced SirT1 activation by a factor of 1.7 times; precisely the opposite effect one is looking for in a product designed to increase longevity.
How Should I Store the Products?
Biotivia products are very stable at room temperature but it will not hurt to refrigerate them. Either way they will last for at least 2 years on the shelf after opening.
